Cardio-fort 30 tbl

FOR THE WELL-BEING OF THE CARDIOVASCULAR SYSTEM

What is the cardiovascular system and what is TN Pharma Cardio-Fort for?

The health of the heart and the entire circulatory system is fundamental to the whole organism because the heart is the engine of life, working 24 hours a day and contracting incessantly pumping blood through blood vessels and thus ensuring all our cells of their vital element: oxygen; for this reason, cardiovascular health remains a major global, daily concern. The enormous prevalence of cardiovascular disease is explained by the increasing prevalence of poor lifestyles; this leads us to conclude that cardiovascular disease is largely preventable, as it recognizes, alongside non-modifiable risk factors (age, sex and familiarity), also modifiable factors, related to behaviors and lifestyles (smoking, alcohol, poor diet, sedentary lifestyle) that are often in turn the cause of diabetes, obesity, hypercholesterolemia, high blood pressure, and metabolic syndrome.

The prevention of cardiovascular diseases is possible only by reducing the "overall individual cardiovascular risk," yes, because the factors that then give rise to such diseases do not depend solely and strictly on the heart organ, but also on a number of factors related to it indirectly.

The Istituto Superiore di Sanità (ISS) has created and made available the Risk Cards which can be used in individuals aged 40 to 69 years, who have had no previous cardiovascular events, who are not pregnant, and who do not have extreme blood pressure and cholesterol values. By knowing an individual's sex, presence or absence of diabetes and smoking habit, age, systolic blood pressure, and cholesterolemia, it is possible to estimate the probability of experiencing a first major cardiovascular event (myocardial infarction or stroke) in the next 10 years. Calculating overall cardiovascular risk is very useful in identifying one's level of risk and taking appropriate preventive interventions.

What each of us can already normally do on a daily basis is to implement simple steps:

• Quit smoking
• Keeping weight under control
• Follow a healthy diet
• Reduce salt intake
• Exercise (the benefits of physical activity on the cardiovascular system are well known)

Each of us should take charge of our own cardiovascular well-being by controlling risk factors, but when the situation needs deeper help, which still does not involve the use of drugs, we can turn to the use of dietary supplements.

In this regard, the TN Pharma Research & Development Team has developed CARDIO-FORT, a dietary supplement that aims to give support in the fight against problems of the 'cardiovascular system.

Let's see what specific ingredients make up the formula of CARDIO-FORT:

CORDIART®

Cordiart® is a registered ingredient, natural fruit rutinoside extract, which promotes healthy circulation. Unlike generic ingredients in this category that focus mainly on cholesterol, a clinical study has demonstrated the beneficial effects ofCordiart® on endothelial function, inflammatory status, and metabolic parameters.

Blood vessels are the interface between the blood and the body and enable the transport of nutrients to the body's cells. The inner lining of the blood vessel, the endothelium, plays a key role in maintaining healthy arteries. With aging, lifestyle, and inflammation, blood vessels stiffen. When the endothelium is not functioning properly, blood vessels lose the ability to fully dilate in response to a change in blood flow and attract more fatty deposits and inflammatory cells; this state is called endothelial dysfunction. Endothelial dysfunction is recognized as an important factor in the development of cardiovascular disease (CVD) such as atherosclerosis, hypertension, and heart failure.

Endothelial dysfunction is commonly associated with reduced nitric oxide (NO) bioavailability due to reduced NO production by the endothelium. NO is a crucial molecule in maintaining vascular health. It largely mediates vasodilation, inhibition of inflammation, and inhibition of platelet adhesion and aggregation.

Cordiart® was tested in two clinical trials to evaluate the benefits on cardiovascular health. The results of the studies showed the threefold action of Cordiart® on arteries. Specifically:

• Maintains arterial flexibility
• Lowers blood pressure
• Reduces plaque formation

It is possible to achieve these three results with a well-known and studied mechanism of action:

Cordiart®, in fact, stimulates the enzyme Endothelial Nitric Oxide Synthase (eNOs) to restore physiological nitric oxide (NO) production. Nitric Oxide sends a signal to the smooth muscles of the vessels causing them to relax. This is not simply a temporary increase in NO levels, rather it allows the blood vessels to dilate "on demand," restoring natural function.

In conclusion, Cordiart® is a unique pharmaceutical grade rutinoside extract derived from fruit with distinctive characteristics:

• CLINICALLY PROVEN HEALTH EFFECTS
• KNOWN MODE OF ACTION
• LOW DAILY DOSE OF 500 MG
• SUPERIOR BIOAVAILABILITY

LEUCOSELECT®PHYTOSOME®

Obtained from the seeds of Vitis vinifera L., Leucoselect® Phytosome® is a smart combination of standardized grape seed extract and sunflower lecithin, with a high concentration of oligomeric proanthocyanidins (OPCs).

It is beneficial for cardiovascular health due to its antioxidant power.

Specifically designed to support normal cardiac function and protect against challenges related to oxidative stress, thanks to the Phytosome® delivery system, Leucoselect® is an innovative formulation that optimizes the bioabsorption of antioxidants.

Due to the presence of OPCs, Leucoselect® Phytosome® has shown relevant biological activity in human studies, with a real positive effect on cardiac status, particularly as it improves plasma antioxidant capacity and protects LDL from oxidation, especially in heavy smokers.

In addition, Leucoselect® Phytosome® can reduce the formation of reactive oxygen compounds (ROS) in people with impaired glucose homeostasis and improve the living conditions and immune function of elderly people.

The uniqueness of Leucoselect® Phytosome® lies in its high content (80%) of smaller OPCs, which are critical for bioactivity because the uptake of procyanidins decreases with the degree of oligomerization. Indeed, the extract has a very specific HPLC profile: it has a very high content of smaller OPCs and is standardized to contain 25-36% proanthocyanidins. In addition, the formulation with Phytosome® technology optimizes bioabsorption.

Phytosome® is the biomimetic strategy for the delivery of natural ingredients, which allows our body to absorb them in the best possible way. The Phytosome® delivery system combines dietary sunflower lecithin with botanicals and natural substances while maintaining the benefits of the original components. Numerous scientific studies have shown that the Phytosome® formulation offers optimized pharmacokinetic profiles and efficacy compared to equivalent compounds not so formulated.

WHITHORNSPIN

Hawthorn is a common shrub that grows wild in the temperate zones of the northern hemisphere (Europe, Asia, America).

In Italy it is widespread throughout the territory, as well as in the plains, it can also be found in the mountains,

Belonging to the Rosaceae family, its name is derived from the Greek kràtaigos, a term that recalls the concept of "strength." It has thorns, and forms ornamental hedges for its beautiful white flowers in spring and red berries that ripen in winter.

Always known as the plant of the heart, it is useful for supporting cardiovascular function

Hawthorn is a source of antioxidants (including oligomeric procyanidins and quercertin), sterols and other compounds of interest to health.

Flavonoids and proanthocyanidols are obtained from the dried flowers and leaves: the former are powerful antioxidants and free radical "scavengers," useful in the prevention of cardiovascular and inflammatory diseases.

Together with proanthocyanidols, a family of polyphenols belonging to the flavonoid class, they have cardioprotective, sedative and antiradical functions.

Cardioprotective action: flavonoids induce dilation of abdominal and, especially, coronary blood vessels that carry blood to the heart, resulting in reduced blood pressure. Useful in cases of mild to moderate hypertension, especially those of nervous origin.

Hawthorn also markedly decreases the frequency of heartbeats, proving useful in angina and all disorders due to hyperexcitability of the heart.

Clinical studies have shown that in heart failure, titrated dry extract of hawthorn can reduce heart rate, ankle swelling, and blood pressure with reduction of symptoms of distress without the appearance of side effects.

Antiradical action: hawthorn is able to trap free radicals by reducing the accumulation of cholesterol in the blood vessel wall, which tends to be deposited after being oxidized. In this way it hinders atherosclerosis.

In cases, for example, of heart failure-a condition in which the heart is unable to pump enough blood to other organs-hawthorn seems to be able to significantly improve the function of the heart muscle, so much so that it also increases the likelihood of physical activity despite the problem with which one is living.

In addition, some studies indicate that hawthorn may help in cases of angina pectoris (a condition caused by reduced blood flow to the heart characterized by the appearance of chest pain) and in cases where high blood pressure needs to be kept under control.

The intake of hawthorn is also suggested to protect health from the increased risks run by the heart and arteries typical of menopause. Suggestions for use of hawthorn, however, go beyond protecting cardiovascular well-being.

BERBERINE

To complete the spectrum of action of CARDIO-FORT we have chosen to use this plant extract, Berberine, which differs from the other ingredients because its action on the cardiovascular system is indirect. Used for centuries in Ayurvedic and Chinese medicine, berberine is an alkaloid found in several plants belonging to the Berberidaceae family and in other plant species. According to recent studies, berberine plays a major role in the prevention of atherosclerotic and degenerative processes in the arteries and in balancing cholesterol, blood pressure and triglyceride levels. In short, a true panacea for theheart and cardiovascular system.

Balanced diet and healthy lifestyle are the basic prerequisites for preserving heart health, but berberine performs its action effectively and without side effects, a quality, the latter, that makes it competitive with traditional drugs, which are effective but insidious in this respect.

Berberine also acts on so-called insulin resistance, which is the loss by tissues of sensitivity to insulin, a regulatory molecule of metabolism. Insulin resistance can result in the eponymous syndrome, also known as metabolic syndrome, a dangerous condition that, by going to alter blood pressure and promoting the accumulation of abdominal fat, plays an active part in the development of cardiovascular disease. The active ingredients of berberine intervene, in these cases, helping the body to keep the level of lipids in the blood under control, preventing their accumulation.
Its intake promotes the restoration of metabolic balance, sheltering us from heart disease. However, it is understood, as mentioned above, that a healthy lifestyle based on regular exercise and a balanced, low-fat diet is essential, especially for heart health.

CARDIO-FORT is an effective and innovative ally for the well-being of the cardiovascular system and the prevention of cardiovascular disease; technologically advanced and safe because it guarantees, through specific analyses, it is a certified GLUTEN-FREE, lactose-free and VEGAN product.

How and when to take Cardio-Fort?

Take 2 tablets daily, with a glass of water.